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Epigenetic Control of Gene Expression(으)로 돌아가기

멜버른 대학교의 Epigenetic Control of Gene Expression 학습자 리뷰 및 피드백

4.8
별점
734개의 평가
205개의 리뷰

강좌 소개

While the human genome sequence has transformed our understanding of human biology, it isn’t just the sequence of your DNA that matters, but also how you use it! How are some genes activated and others are silenced? How is this controlled? The answer is epigenetics. Epigenetics has been a hot topic for research over the past decade as it has become clear that aberrant epigenetic control contributes to disease (particularly to cancer). Epigenetic alterations are heritable through cell division, and in some instances are able to behave similarly to mutations in terms of their stability. Importantly, unlike genetic mutations, epigenetic modifications are reversible and therefore have the potential to be manipulated therapeutically. It has also become clear in recent years that epigenetic modifications are sensitive to the environment (for example diet), which has sparked a large amount of public debate and research. This course will give an introduction to the fundamentals of epigenetic control. We will examine epigenetic phenomena that are manifestations of epigenetic control in several organisms, with a focus on mammals. We will examine the interplay between epigenetic control and the environment and finally the role of aberrant epigenetic control in disease. All necessary information will be covered in the lectures, and recommended and required readings will be provided. There are no additional required texts for this course. For those interested, additional information can be obtained in the following textbook. Epigenetics. Allis, Jenuwein, Reinberg and Caparros. Cold Spring Harbour Laboratory Press. ISBN-13: 978-0879697242 | Edition: 1 The course will re-open in 2022....

최상위 리뷰

MM

2018년 10월 1일

This was an excellent course. All the material was well presented and the explanation of the sometimes complex subject matter was clear and understandable. Thank you for an great learning experience.

NN

2021년 8월 1일

This is the best course on coursera, 10/10. I wish it was longer and I could take it all over again. you will need background knowledge for this course but it is an amazing course and I will miss it.

필터링 기준:

Epigenetic Control of Gene Expression의 201개 리뷰 중 201~201

교육 기관: Dong M

2017년 7월 31일

the whole lecture given by the lecturer is so confused. And really boring by her monotone. There is almost no connections between slides and the explanation is so unconvinced. Also, it will be better if the lecture can help recall previous slides when talking about relative definition or trying to explain something. wasted my time to be honest