About this Course
4.6
29개의 평가
12개의 리뷰

다음의 8/8개 강좌

100% 온라인

지금 바로 시작해 나만의 일정에 따라 학습을 진행하세요.

탄력적인 마감일

일정에 따라 마감일을 재설정합니다.

완료하는 데 약 21시간 필요

권장: 8 weeks of study, 2-4 hours/week...

영어

자막: 영어

다음의 8/8개 강좌

100% 온라인

지금 바로 시작해 나만의 일정에 따라 학습을 진행하세요.

탄력적인 마감일

일정에 따라 마감일을 재설정합니다.

완료하는 데 약 21시간 필요

권장: 8 weeks of study, 2-4 hours/week...

영어

자막: 영어

강의 계획 - 이 강좌에서 배울 내용

1
완료하는 데 1시간 필요

Introduction

In this first week, we'll introduce the project and get you oriented to the tasks that you'll be performing over the next several weeks. ...
1 video (Total 3 min), 6 readings
6개의 읽기 자료
Welcome10m
The big question10m
What you will be doing in this capstone project10m
Passing the Capstone10m
Why re-analysis?10m
Why is this so hard?10m
2
완료하는 데 1시간 필요

Introduction to the Dataset - Andrew Jaffe

This week, we'll really dig into the dataset by providing an introduction from Andrew Jaffe, the lead scientist on the analysis. You should also be looking ahead to Task 2, which is due in Week 4; the alignment will take a long time to perform, so you should start early....
1 video (Total 4 min), 3 readings
1개의 동영상
3개의 읽기 자료
Phenotype information10m
Getting the data from SRA10m
Which samples to use10m
3
완료하는 데 1시간 필요

Understand the Problem

The purpose of genomic data science is to answer fundamental questions in biology. Before starting on the data analysis process, the first step is always to understand the scientific question you are trying to answer. Don't forget to stay on top of the alignment task due in Week 4; it will take a long time to accomplish and shouldn't be put off....
1 video (Total 7 min), 1 reading, 1 quiz
1개의 동영상
1개의 읽기 자료
Task 1 Instructions10m
1개 연습문제
Understand the problem18m
4
완료하는 데 2시간 필요

Alignment

Once you have understood the problem, the next step is to obtain the raw data so that you can perform your analysis. ...
1 quiz
5
완료하는 데 2시간 필요

QC the Alignment

Now you have aligned the data, the next step is to do some quality control to make sure that the data are in good shape. ...
1 quiz
6
완료하는 데 2시간 필요

Get Feature Counts

Now that you have performed alignment and quality control, the next step is to calculate the abundance of every gene in every sample....
1 quiz
7
완료하는 데 2시간 필요

Exploratory Analysis

After summarizing your genomic data the next step is to load the data into R for analysis with Bioconductor....
1 quiz
8
완료하는 데 2시간 필요

Statistical Analysis

The next step is to perform a statistical analysis to detect genes that are differentially expressed. ...
1 quiz
9
완료하는 데 4시간 필요

Gene Set Analysis

In task 6, we have identified genes differentially expressed between fetal and adult brain. Now we will examine these results in a wider context. ...
2 quizzes
10
완료하는 데 2시간 필요

Describe Your Analysis

The next step is to document your work. One of the major issues in genomic data science is that there are so many steps in the process. If these steps are not documented well the result can be major problems. ...
1 quiz
4.6
12개의 리뷰Chevron Right

최상위 리뷰

대학: FAJul 24th 2016

Great course! I can't think of a better way of putting together all we learned during the whole specialisation in one real world research project...

대학: PSDec 20th 2018

An excellent challenge. Previous courses everything was neatly packaged before you start. This course teaches you how to get there.

강사

Avatar

Jeff Leek, PhD

Associate Professor, Biostatistics
Bloomberg School of Public Health
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Kasper Daniel Hansen, PhD

Assistant Professor, Biostatistics and Genetic Medicine
Bloomberg School of Public Health

존스홉킨스대학교 정보

The mission of The Johns Hopkins University is to educate its students and cultivate their capacity for life-long learning, to foster independent and original research, and to bring the benefits of discovery to the world....

Genomic Data Science 전문 분야 정보

This specialization covers the concepts and tools to understand, analyze, and interpret data from next generation sequencing experiments. It teaches the most common tools used in genomic data science including how to use the command line, Python, R, Bioconductor, and Galaxy. The sequence is a stand alone introduction to genomic data science or a perfect compliment to a primary degree or postdoc in biology, molecular biology, or genetics. To audit Genomic Data Science courses for free, visit https://www.coursera.org/jhu, click the course, click Enroll, and select Audit....
Genomic Data Science

자주 묻는 질문

  • 강좌에 등록하면 바로 모든 비디오, 테스트 및 프로그래밍 과제(해당하는 경우)에 접근할 수 있습니다. 상호 첨삭 과제는 이 세션이 시작된 경우에만 제출하고 검토할 수 있습니다. 강좌를 구매하지 않고 살펴보기만 하면 특정 과제에 접근하지 못할 수 있습니다.

  • 강좌를 등록하면 전문 분야의 모든 강좌에 접근할 수 있고 강좌를 완료하면 수료증을 취득할 수 있습니다. 전자 수료증이 성취도 페이지에 추가되며 해당 페이지에서 수료증을 인쇄하거나 LinkedIn 프로필에 수료증을 추가할 수 있습니다. 강좌 내용만 읽고 살펴보려면 해당 강좌를 무료로 청강할 수 있습니다.

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