This course introduces you to the basic biology of modern genomics and the experimental tools that we use to measure it. We'll introduce the Central Dogma of Molecular Biology and cover how next-generation sequencing can be used to measure DNA, RNA, and epigenetic patterns. You'll also get an introduction to the key concepts in computing and data science that you'll need to understand how data from next-generation sequencing experiments are generated and analyzed.
This is the first course in the Genomic Data Science Specialization.
이 강좌는 Genomic Data Science 전문 분야의 일부입니다.
Introduction to Genomic Technologies
4.5
(1,560개의 평가)
30,495명이 이미 등록했습니다!
제공자:
강의 계획 - 이 강좌에서 배울 내용
주
1완료하는 데 2시간 필요
Overview
In this Module, you can expect to study topics of "Just enough molecular biology", "The genome", "Writing a DNA sequence", "Central dogma", "Transcription", "Translation", and "DNA structure and modifications".
8 videos (Total 81 min), 2 readings, 1 quiz
8개의 동영상
What Is Genomics?7m
What Is Genomic Data Science?8m
Just Enough Cell Biology8m
Important Molecules in Molecular Biology7m
The Human Genome Project17m
Molecular Biology Structures9m
From Genes to Phenotypes9m
2개의 읽기 자료
Syllabus10m
Pre-Course Survey10m
1개 연습문제
Quiz 1: Overview and Molecular Biology20m
주
2완료하는 데 1시간 필요
Measurement Technology
In this module, you'll learn about polymerase chain reaction, next generation sequencing, and applications of sequencing.
3 videos (Total 25 min), 1 quiz
1개 연습문제
Quiz 2: Measurement Technology20m
주
3완료하는 데 1시간 필요
Computing Technology
The lectures for this module cover a few basic topics in computing technology. We'll go over the foundations of computer science, algorithms, memory and data structures, efficiency, software engineering, and computational biology software.
6 videos (Total 39 min), 1 quiz
6개의 동영상
Algorithms4m
Memory and Data Structures6m
Efficiency3m
Software Engineering8m
What is Computational Biology Software11m
1개 연습문제
Quiz 3: Computing Technology20m
주
4완료하는 데 2시간 필요
Data Science Technology
In this module on Data Science Technology, we'll be covering quite a lot of information about how to handle the data produced during the sequencing process. We'll cover reproducibility, analysis, statistics, question types, the central dogma of inference, analysis code, testing, prediction, variation, experimental design, confounding, power, sample size, correlation, causation, and degrees of freedom.
10 videos (Total 55 min), 2 readings, 2 quizzes
10개의 동영상
What Went Wrong?4m
The Central Dogma of Statistics3m
Data Sharing Plans4m
Getting Help with Statistics2m
Plotting Your Data5m
Sample Size and Variability7m
Statistical Significance6m
Multiple Testing7m
Study Design, Batch Effects, and Confounding7m
2개의 읽기 자료
Course Project Instructions and Reading10m
Post-Course Survey10m
2개 연습문제
Quiz 4: Data Science Technology20m
Course Project20m
4.5
256개의 리뷰35%
이 강좌를 수료한 후 새로운 경력 시작하기
29%
이 강좌를 통해 확실한 경력상 이점 얻기
최상위 리뷰
Relatively nice introduction course, contents are maybe rather limited, yet as an instructive course, it does provide a clear overview which correlates well with the required answers for the quizzes!
Very good introductory course. It's a lot of material to cover for a newbie, but if you have some background, you will find you progress pretty quickly. Enjoyable, engaging, fun and useful.
강사
Steven Salzberg, PhD
ProfessorBiomedical Engineering, Computer Science, and Biostatistics
Jeff Leek, PhD
Associate Professor, BiostatisticsBloomberg School of Public Health
존스홉킨스대학교 정보
The mission of The Johns Hopkins University is to educate its students and cultivate their capacity for life-long learning, to foster independent and original research, and to bring the benefits of discovery to the world.
Genomic Data Science 전문 분야 정보
This specialization covers the concepts and tools to understand, analyze, and interpret data from next generation sequencing experiments. It teaches the most common tools used in genomic data science including how to use the command line, Python, R, Bioconductor, and Galaxy. The sequence is a stand alone introduction to genomic data science or a perfect compliment to a primary degree or postdoc in biology, molecular biology, or genetics.
To audit Genomic Data Science courses for free, visit https://www.coursera.org/jhu, click the course, click Enroll, and select Audit.
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