About this Course
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지금 바로 시작해 나만의 일정에 따라 학습을 진행하세요.

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완료하는 데 약 14시간 필요

권장: 2-4 hours/week...

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자막: 영어

100% 온라인

지금 바로 시작해 나만의 일정에 따라 학습을 진행하세요.

탄력적인 마감일

일정에 따라 마감일을 재설정합니다.

완료하는 데 약 14시간 필요

권장: 2-4 hours/week...

영어

자막: 영어

강의 계획 - 이 강좌에서 배울 내용

1
완료하는 데 3시간 필요

UNIT 1: INTRODUCTION TO PERSONALIZED MEDICINE

The first module of this course will focus on introducing the concept of personalized medicine. We will very briefly review fundamentals of genetics as these apply to personalized medicine (DNA structure; RNA; protein structures; function of DNA; coding; DNA variations; types of genetic variants), as well as review statistical concepts and skills important to clinical data analysis (odds ratios, relative risk, P values, multiple testing, sensitivity, specificity, ROCs). In Module 2 we will explore drug actions and reactions as we look closely at the general mechanisms underlying variability in drug responses, drug metabolism and transport, and genetic variability in drug-handling molecules....
11 videos (Total 120 min), 1 reading, 1 quiz
11개의 동영상
Introduction to Personalized Medicine11m
Genetics Definitions, Part I14m
Genetics Definitions, Part II & Types of Genetic Variants15m
Data Analysis, Part I: What is a Good Study?12m
Data Analysis, Part II: What is a Good Test?7m
Introduction to Drug Therapy and General Mechanisms Underlying Variability in Drug Responses13m
Variability in Drug Therapy15m
Drug Metabolism & Transport13m
Genetic Variability in Drug-Handling Molecules10m
**Inside VUMC: The Promise of Personalized Medicine1m
1개의 읽기 자료
About this course10m
1개 연습문제
Introduction to Personalized Medicine12m
2
완료하는 데 2시간 필요

UNIT 2: STUDYING GENETIC VARIATION

Module 3 focuses on how we study genetic variation. We'll start by looking at families and populations. Topics that will be introduced include family history and inheritance patterns, ancestry, and linkage. Then in Module 4 we shift our focus to studying the contemporary techniques and technologies used to study genetic variation, including genome-wide association and sequencing....
7 videos (Total 104 min), 1 quiz
7개의 동영상
Ancestry: Genetic Variation Across Generations and Geography17m
Finding Disease-Associated Genes: Linkage10m
**Inside VUMC: From Phenotype to Genotype and Back: Studying Heart Disease in Families1m
Genome-Wide Association25m
Sequencing28m
**Inside VUMC: History of Sequencing Technologies1m
1개 연습문제
Studying Genetic Variation12m
3
완료하는 데 3시간 필요

UNIT 3: CASE STUDIES IN PERSONALIZED MEDICINE, PART 1

In Module 5 we will begin to discuss specific cases as these apply to personalized medicine. We will first look very closely at a case of familial hypercholesterolemia as we investigate how we use genomic medicine to move from a rare disease to a common medication, using genomics to find new drug targets, and a discussion of the side effects of statin therapy. In Module 6 we will look at a collection of "high risk pharmacogenetics"cases that illustrate adverse reactions due to drug metabolism and variable drug responses....
13 videos (Total 174 min), 1 quiz
13개의 동영상
Using Genomics to Find New Drug Targets: Familial Hypercholesterolemia16m
Muscle Pains During Statin Therapy (Myopathy)13m
HLA-Mediated Immune Reactions (Skin Rash)9m
Long QT Syndromes, Part 115m
Long QT Syndromes, Part 218m
**Inside VUMC: Studying Cardiac Arrhythmias in Cells4m
A Second Heart Attack a Month After a First15m
Headache During Venlafaxine (Antidepressant)16m
Respiratory Arrest After Tonsillectomy10m
A Bleeding Complication 5 Days After Starting Warfarin21m
**Inside VUMC: Genotyping1m
Drug Metabolism and Variable Drug Responses – Four More Examples17m
1개 연습문제
Case Studies, Part I16m
4
완료하는 데 2시간 필요

UNIT 4: CASE STUDIES IN PERSONALIZED MEDICINE, PART 2

Module 7 continues our focus on case studies with a look at some cases that illustrate how personalized medicine informs treatment decisions related to specific diseases/conditions. These include cystic fibrosis, Marfan syndrome, heart failure, neuropsychiatric diseases, and diabetes. Three cases/lessons focus specifically on how genomic medicine informs testing for and treatment of cancer. ...
9 videos (Total 119 min), 1 quiz
9개의 동영상
Marfan Syndrome11m
A Case of Idiopathic Heart Failure16m
Personalizing Care in Neuropsychiatric Disease18m
Personalizing Care in Diabetes21m
Genomics to Subtype Cancer11m
A Family Member With Breast Cancer14m
A Family Member With Colon Cancer11m
**Inside VUMC: Organizing Infrastructure to Support Genetic Testing Decisions1m
1개 연습문제
Case Studies, Part II10m
4.8
37개의 리뷰Chevron Right

17%

이 강좌를 수료한 후 새로운 경력 시작하기

22%

이 강좌를 통해 확실한 경력상 이점 얻기

29%

급여 인상 또는 승진하기

최상위 리뷰

대학: NJApr 9th 2019

The course is very useful for all physicians to diagnoise the disorder and to suggest the solution for their problem and also can explain the cause of the disorder from the root that;s genome.

대학: VLFeb 25th 2018

This is a really great course it was very informative, interesting and well structured and I enjoyed the lessons, Prof. Roden did a really great job in this course. Thank you!

강사

Avatar

Dan Roden, M.D.

Professor of Medicine and Pharmacology
Assistant Vice Chancellor for Personalized Medicine

밴더빌트 대학교 정보

Vanderbilt University, located in Nashville, Tenn., is a private research university and medical center offering a full-range of undergraduate, graduate and professional degrees....

자주 묻는 질문

  • 강좌에 등록하면 바로 모든 비디오, 테스트 및 프로그래밍 과제(해당하는 경우)에 접근할 수 있습니다. 상호 첨삭 과제는 이 세션이 시작된 경우에만 제출하고 검토할 수 있습니다. 강좌를 구매하지 않고 살펴보기만 하면 특정 과제에 접근하지 못할 수 있습니다.

  • 수료증을 구매하면 성적 평가 과제를 포함한 모든 강좌 자료에 접근할 수 있습니다. 강좌를 완료하면 전자 수료증이 성취도 페이지에 추가되며, 해당 페이지에서 수료증을 인쇄하거나 LinkedIn 프로필에 수료증을 추가할 수 있습니다. 강좌 콘텐츠만 읽고 살펴보려면 해당 강좌를 무료로 청강할 수 있습니다.

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