Large-scale biology projects such as the sequencing of the human genome and gene expression surveys using RNA-seq, microarrays and other technologies have created a wealth of data for biologists. However, the challenge facing scientists is analyzing and even accessing these data to extract useful information pertaining to the system being studied. This course focuses on employing existing bioinformatic resources – mainly web-based programs and databases – to access the wealth of data to answer questions relevant to the average biologist, and is highly hands-on.
제공자:
이 강좌에 대하여
최근 조회 113,303회
학습자 경력 결과
24%
가 이 강좌를 수료한 후 새로운 커리어를 시작함
30%
가 이 강좌를 통해 확실한 경력상 이점을 얻음
17%
가 급여 인상 또는 승진 성취
공유 가능한 수료증
완료 시 수료증 획득
100% 온라인
지금 바로 시작해 나만의 일정에 따라 학습을 진행하세요.
다음 특화 과정의 4개 강좌 중 1번째 강좌:
유동적 마감일
일정에 따라 마감일을 재설정합니다.
초급 단계
완료하는 데 약 20시간 필요
영어
자막: 영어
귀하가 습득할 기술
Genetic AnalysisBioinformatics AnalysisEvolutionComparative Genomics
학습자 경력 결과
24%
가 이 강좌를 수료한 후 새로운 커리어를 시작함
30%
가 이 강좌를 통해 확실한 경력상 이점을 얻음
17%
가 급여 인상 또는 승진 성취
공유 가능한 수료증
완료 시 수료증 획득
100% 온라인
지금 바로 시작해 나만의 일정에 따라 학습을 진행하세요.
다음 특화 과정의 4개 강좌 중 1번째 강좌:
유동적 마감일
일정에 따라 마감일을 재설정합니다.
초급 단계
완료하는 데 약 20시간 필요
영어
자막: 영어
제공자:
토론토 대학교
Established in 1827, the University of Toronto is one of the world’s leading universities, renowned for its excellence in teaching, research, innovation and entrepreneurship, as well as its impact on economic prosperity and social well-being around the globe.
강의 계획 - 이 강좌에서 배울 내용
완료하는 데 3시간 필요
NCBI/Blast I
In this module we'll be exploring the amazing resources available at NCBI, the National Centre for Biotechnology Information, run by the National Library of Medicine in the USA. We'll also be doing a Blast search to find similar sequences in the enormous NR sequence database. We can use similar sequences to infer homology, which is the primary predictor of gene or protein function.
완료하는 데 3시간 필요
4개 동영상 (총 51분), 4 개의 읽기 자료, 1 개의 테스트
4개의 읽기 자료
Acknowledgements10m
Course Logistics10m
Lecture Materials10m
Lab 1 -- Exploring NCBI1시간 30분
1개 연습문제
Lab 1 Quiz30m
완료하는 데 3시간 필요
Blast II/Comparative Genomics
In this module we'll continue exploring the incredible resources available at NCBI, the National Centre for Biotechnology Information. We will be performing several different kinds of Blast searches: BlastP, PSI-Blast, and Translated Blast. We can use similar sequences identified by such methods to infer homology, which is the primary predictor of gene or protein function. We'll also be comparing parts of the genomes of a couple of different species, to see how similar they are.
완료하는 데 3시간 필요
4개 동영상 (총 58분), 2 개의 읽기 자료, 1 개의 테스트
2개의 읽기 자료
Lecture Materials10m
Lab 2 -- Advanced Blast and Comparative Genomics1시간 30분
1개 연습문제
Lab 2 Quiz30m
완료하는 데 3시간 필요
Multiple Sequence Alignments
In this module we'll be doing multiple sequence alignments with Clustal (as implemented in MEGA), DiAlign, and MAFFT. Multiple sequences alignments can tell you where in a sequence the conserved and variable regions are, which is important for understanding the biology of the sequences under investigation. It also has practical applications, such as being able to design PCR primers that will amplify sequences from a number of different species, for example.
완료하는 데 3시간 필요
4개 동영상 (총 44분), 2 개의 읽기 자료, 1 개의 테스트
2개의 읽기 자료
Lecture Materials10m
Lab 3 -- Multiple Sequence Alignment1시간 30분
1개 연습문제
Lab 3 Quiz30m
완료하는 데 1시간 필요
Review: NCBI/Blast I, Blast II/Comparative Genetics, and Multiple Sequence Alignments
완료하는 데 1시간 필요
1개 연습문제
Quiz: Modules 1-330m
검토
BIOINFORMATIC METHODS I의 최상위 리뷰
ED 제공2017년 4월 26일
Great course. All lectures provide a biological context for the tools you learn in the labs. The labs themselves provide a great introduction to the many tools available for bioinformatic analysis.
FJ 제공2017년 2월 5일
The videos were very clear on how to use various bioinformatic tools. I found no difficulty in understanding them. Really enjoyed the course. Looking forward to the next part of this course!
RG 제공2017년 11월 4일
I enjoyed doing the course. It is exciting to see how much one can learn from a few gene or protein sequences. Thank you for making the course understandable to a beginner in bioinformatics!
PS 제공2017년 7월 8일
A fully recommended course for those who wish to understand the basics and strengthen their skills in Bioinformatics. A well-designed and precise course. Thank you Dr. Nicholas Provart. :-)
Plant Bioinformatic Methods 특화 과정 정보
The past 15 years have been exciting ones in plant biology. Hundreds of plant genomes have been sequenced, RNA-seq has enabled transcriptome-wide expression profiling, and a proliferation of "-seq"-based methods has permitted protein-protein and protein-DNA interactions to be determined cheaply and in a high-throughput manner. These data sets in turn allow us to generate hypotheses at the click of a mouse or tap of a finger.The Plant Bioinformatics Specialization on Coursera introduces core bioinformatic competencies and resources, such as NCBI's Genbank, Blast, multiple sequence alignments, phylogenetics in Bioinformatic Methods I, followed by protein-protein interaction, structural bioinformatics and RNA-seq analysis in Bioinformatic Methods II. In Plant Bioinformatics we cover 33 plant-specific online tools from genome browsers to transcriptomic data mining to promoter/network analyses and others. Last, a Plant Bioinformatics Capstone uses these tools to hypothesize a biological role for a gene of unknown function, summarized in a written lab report.This specialization is useful to any modern plant molecular biologist wanting to get a feeling for the incredible scope of data available to researchers. A small amount of R programming is introduced in Bioinformatic Methods II, but most of the tools are web applications. It is recommended that you have access to a laptop or desktop computer for running these as they may not work as mobile applications on your phone or tablet.
자주 묻는 질문
When will I have access to the lectures and assignments?
Access to lectures and assignments depends on your type of enrollment. If you take a course in audit mode, you will be able to see most course materials for free. To access graded assignments and to earn a Certificate, you will need to purchase the Certificate experience, during or after your audit. If you don't see the audit option:
The course may not offer an audit option. You can try a Free Trial instead, or apply for Financial Aid.
The course may offer 'Full Course, No Certificate' instead. This option lets you see all course materials, submit required assessments, and get a final grade. This also means that you will not be able to purchase a Certificate experience.
What will I get if I subscribe to this Specialization?
When you enroll in the course, you get access to all of the courses in the Specialization, and you earn a certificate when you complete the work. Your electronic Certificate will be added to your Accomplishments page - from there, you can print your Certificate or add it to your LinkedIn profile. If you only want to read and view the course content, you can audit the course for free.
What is the refund policy?
If you subscribed, you get a 7-day free trial during which you can cancel at no penalty. After that, we don’t give refunds, but you can cancel your subscription at any time. See our full refund policy.
Is financial aid available?
Yes, Coursera provides financial aid to learners who cannot afford the fee. Apply for it by clicking on the Financial Aid link beneath the "Enroll" button on the left. You'll be prompted to complete an application and will be notified if you are approved. You'll need to complete this step for each course in the Specialization, including the Capstone Project. Learn more.
궁금한 점이 더 있으신가요? 학습자 도움말 센터를 방문해 보세요.
© 2020 Coursera Inc. All rights reserved.
